Application example of spray drying technology in traditional Chinese medicine pharmacy - one-step spray drying granulation of traditional Chinese medicine liquid Spray drying has been used in industry for more than 100 years. At first, because of the low thermal efficiency of this process, it is only used for high-priced products (such as milk powder) or products that are not suitable for such drying methods (such as heat-sensitive biochemical products). In recent decades, due to the continuous research and development of spray drying, the spray device has been gradually improved and the thermal process has been continuously improved, making this process not only suitable for fine operations under strict sterilization conditions (such as pharmaceutical manufacturing), but also applicable. Products with high tonnage (such as ceramics, synthetic detergents, chemical fertilizers, etc.), and its application range is expanding. With the in-depth study of the atomization mechanism, the movement of droplets in the gas stream, the heat transfer and the mass transfer process, the size and capacity of the spray dryer have been greatly increased. This not only facilitates the production of high-tonnage products, but also saves investment costs and operating costs, thereby improving the economic performance of the spray dryer. For example, a spray dryer used in the production of synthetic washing powder in a factory in China has a tower diameter of 6 m, a total height of 34 m, and a synthetic washing powder output of 4000 to 5000 kgöh. Another example is a spray dryer used in the production of ammonium nitrate by a chemical fertilizer plant. The tower diameter is 16m, the tower height is 60m, and the output can reach 1000t per day [4]. The general process for the production of traditional Chinese medicine preparations is still characterized by the production of a large amount of extract. The application of spray drying technology can concentrate, dry, pulverize and even granulate the extract in one step, avoiding the long elapsed time and dry quality of the traditional evaporation operation and vacuum drying process. The shortcomings of the difference greatly improve the production efficiency, and at the same time relatively improve the quality of the dried product. The spray-dried traditional Chinese medicine extract is powdery or granular, which has better fluidity, less water content, uniform texture and dissolution than the traditional dried product. Good performance, can be directly used for the formation of tablets, granules, capsules. However, in most of the traditional Chinese medicine manufacturing processes, there are many steps for extracting parts. First, it is concentrated by multi-effect vacuum, and then concentrated by a sandwich pot. The third step is mixed with auxiliary materials, then granulated, and finally dried into an dry product by an oven. , a total of five steps. The whole production process uses many equipments, and the exposed air and transport times are many, the work efficiency is low, the energy consumption is large, especially in the concentration stage. To this end, we have developed a one-step spray drying granulation process and equipment for Chinese medicine liquid, and directly made the dilute liquid into the dry product of traditional Chinese medicine. The whole process is completed in a sealed tower, and the processing environment is more suitable for the internationally implemented GM P requirements (drugs). Production specifications), replacing traditional processes and greatly improving work efficiency. The production of finished or semi-finished products in the same tower solves the gap between traditional processes and international GMP requirements, and can be produced as an efficient and energy-saving device. Main process of one-step spray drying granulation of traditional Chinese medicine liquid The process of one-step granulation of spray drying of traditional Chinese medicine liquid is as follows: the quantitative dry auxiliary particles are added to the spiral feed inlet, and the upper part enters the drying tower, and the filtered air is heated by the heater to enter from the bottom of the drying tower; the hot air enters The dry granules to be added later form a boiling layer, and the auxiliary granules are heated to a specified temperature to start the air compressor. After the medicinal liquid is pressurized by the compressed air in the storage tank, it is atomized by the nozzle and compressed air, and the squirting liquid is sprayed. Adsorbed in the material of the boiling layer; at the same time, the stirring device is continuously stirred, and the particles of the boiling layer dried by the hot air are gradually increased until the discharge port is discharged; the exhaust gas is discharged from the top of the tower through the induced draft fan.