Piglet edema, also known as E. coli toxemia, occurs most often in suckling piglets. Feed intake contains high protein or feed mutations that cause hemolytic E. coli toxins to cause acute, sporadic infectious diseases. The main features are general or partial paralysis, ataxia, and edema. 1. Epidemic features The disease occurs most frequently in spring and autumn, with high prevalence in strong weaned piglets. Without regularity, the incidence rate is about 50%, and the mortality rate is above 80%. Most of the hemolytic E. coli is present in the intestine of sows, contaminating the feed, drinking water, and feeding environment through excreta and passing through the digestive tract. Such as feed mutations, poor sanitation, sudden temperature changes, lack of minerals and vitamins in feed can often induce the disease. 2. The main cause of swine fever caused by pathological analysis is related to digestive enzymes. After the birth of the piglets, the gastrointestinal function is not perfect, and various digestive enzymes are produced less. When a large amount of concentrate feeds for the first time, the body produces a stress reaction, which leads to the inability of the feed enzyme to transform, thereby causing symptoms of intestinal inflammation and bowel edema. Intestinal edema produces a large amount of unsaturated acid, which is transmitted through the blood and medulla to the brain. The inflammatory reaction causes cerebral palsy and causes limb ataxia. 3. The clinical symptoms have a very short incubation period. They will develop in several hours and fall into 4 types. The most urgent type: sudden blood stasis, fecal odor, mixed with necrotic tissue and air bubbles, hi lying, body temperature is not high, increasing weight loss, abdominal skin black before death, there are no symptoms to death; acute type: red row of brown Watery stools, rapid dehydration failure; sub-emergency type: persistent diarrhea, discharge yellow soft stools, later into a liquid, containing necrotic tissue debris, dehydration failure; chronic type: intermittent diarrhea, gray stool yellow The anus, tail and hindquarters are covered with dirt. The sick pigs are still in good spirits and die or become stiff pigs after a few weeks. 4. Pathological changes Necrotic lesions in the intestine, edema in the duodenum, caecum and colon, mesenteric hyperemia. Liver, spleen and kidney degeneration. The liver was dark purple; the mesenteric lymph nodes were swollen; the intermedullary medullary and edema. 5.Prevent antenatal thorough cleaning of the delivery room and thoroughly disinfect the ground and utensils; sows are injected intramuscularly with 5 to 10 milliliters of inactivated red piglet vaccine 30 days and 15 days before delivery. The sows were injected with 20-30 ml of compound sulfa-6-methoxyxanthine injection 2 days before delivery, 2 times a day for 2 days. Before feeding the food feed, multiple enzyme tablets were added. According to the intake, 10 tablets of enzyme tablets were added daily; the initial supplement of the feed was less, gradually adapting gradually to increase. 6. Treatment of 1 streptomycin, 100,000 units per kilogram of body weight in the early stage alone. 2040 ml of 25% glucose solution, 100,000 units of gentamicin, 10 ml of dexamethasone, and 4 mg of atropine sulfate were intravenously injected once a day for 3 days. 3 sulfadiazine 10 to 20 ml intramuscularly, once daily, once every 3 days. Zhucheng Tongxi Commercial And Trade Co.,Ltd. , https://www.blackgarlicgroup.com