With the rapid development of the feed industry, in order to prevent livestock and poultry diseases, promote animal growth and improve feed utilization, a large number of chemical synthesis feed additives and chemicals, such as antibiotics, protractor and preservatives, are commonly used in feed. The application of these additives has played a certain role in promoting the development of animal husbandry, but it has also brought negative effects, especially the large-scale use of antibiotics. The resulting drug resistance and drug residues have caused great harm to human health. It has aroused the concern and worries of scientific and technological workers and consumers. With China's accession to the World Trade Organization and the improvement of China's meat food hygiene standards, feed safety is a basic condition for ensuring the safety of animal foods. The development of pollution-free green foods is also a top priority for the livestock industry. In order to explore the source of feed additives and ensure the safety of livestock and poultry products, many scholars have turned their attention to natural herbal feed additives. It has unique features, good effects, and no residue, no resistance to drugs, no pollution, etc. Greatly favored. Mechanism of Action of Natural Chinese Herbal Feed Additives Increase appetite and growth Natural Chinese herbal medicine contains a variety of biologically active substances and growth-promoting factors, which promote the growth and development of animals by enhancing the digestion and absorption of nutrients and the anabolic metabolism in the body. Improve immune function Certain natural Chinese herbal medicines contain biologically active substances that can promote cellular immunity and humoral immunity in animals, thereby enhancing resistance and resistance to stress. Antibacterial deworming to maintain the body's health status Natural Chinese herbal medicine contains a variety of biologically active substances and disease resistance factors, which can prevent and treat diseases, increase survival rate and reduce mortality. The antibacterial mechanism of natural Chinese herbal medicines is different from that of antibiotics. Antibiotics act directly on bacteria to kill them. However, long-term use of antibiotics can cause resistance to pathogenic microorganisms. The natural Chinese herbal medicine restores the body's normal physiological condition (ie, restores the yin and yang balance) through the conditioning of cultivating evils. Natural Chinese herbal medicine contains multiple active factors that can interfere with the metabolism of pathogenic microorganisms, thereby effectively suppressing and killing. Kill pathogenic microorganisms. Improve the quality of animal products such as egg meat, which is related to the natural Chinese herbal medicine containing a variety of biological active substances. Environmental protection effect Artificially manufactured chemical toxicants cause environmental pollution, and chemical synthesis drugs and additives account for a considerable proportion of the pollution, while natural Chinese herbal medicines do not pollute the environment due to non-toxic side effects. Application of Natural Chinese Herbal Additives in Feed Production Application in Livestock and Poultry Breeding: It has been reported that additives such as Phellodendron, Isatis root, garlic, etc. are added to broiler diets at 0.3%. The test results show that the weight gain and survival rate of the test group are higher than those of the control group (P). Application in disease prevention and improvement of immunity: According to reports, the effect of 0.3% dose of unilateral huangqi as feed additive on the immune function of chicks (day 0 to day 56) suggests that the test group has peripheral blood T The normal lymphocyte and lymphocyte transformation rate were greater than those of the control group (P Characteristics and Advantages of Natural Chinese Herbal Feed Additives Natural, pollution-free, conducive to environmental protection Natural Chinese herbal medicines retain their natural structure and activity. Even if they need to be processed, it is not easy to destroy their natural characteristics. After being used, their waste will not pollute the environment. After being abandoned, they can also return to nature and participate in ecological balance. Versatility Each natural Chinese herbal medicine contains ten, several dozen, or even hundreds of organic ingredients. According to the “structure-activity theory†of chemical drugs, each ingredient structure plays an effective role, namely, “one structure and one effectâ€. Natural Chinese herbal medicine has a variety of compositional structures, so it has a variety of effects. For example, Hawthorn has now identified more than 70 components, as well as some unknown factors and biologically active substances. Has been confirmed in clinical practice, Hawthorn helps digestion and absorption, is conducive to cardiovascular activities and has anti-tumor cell growth and other effects. Bidirectional (phase) regulation The functions of tissues and organs are often expressed as (phase) or state with two distinct functions: excitement (enhancement) and inhibition (lower). Western medicine generally can only have a single function to effect, or be excited or inhibited, that is, a one-way effect, because it is only a single component. Natural Chinese herbs are different. Each natural Chinese herbal medicine contains two components that have opposite effects. When the body tissues and organs are in different functional states, it can have different effects on its imbalanced pathology, that is, it has a two-way adjustment effect on different functions of the same tissue and organ, that is, it has an inhibitory effect when excited, and it has an excitatory effect when inhibited. Until it is adjusted to a normal state. Preventing Microorganisms from Producing Drug Resistance: Chinese herbal medicines have non-specific antibacterial effects, which not only can directly inhibit bacteria sterilization but also do not produce drug resistance. The mechanisms of microbial resistance are mutations. Under unfavorable conditions, they can rapidly undergo changes and variations in morphology, structure, antigenicity, virulence, and metabolism, and these mutations can be inherited. The antibacterial effects of natural Chinese herbal medicines, a small number of which contain an antibacterial active ingredient directly act on the bacteria, such as berberine in berberine, astragaloside in astragalus, etc. And most of the antibacterial action mechanism is to stimulate the mobilization of the presence of antibacterial agents in animals, such as phagocytosis, barriers, non-specific serocin, lysozyme, complement, interferon and other functional activities, eliminating the destruction of bacteria and tissues. The role of the body to promote recovery, enhance non-specific immune function, so the natural Chinese herbal medicine will not make bacteria resistant. Overall regulation The role of matter on the body is divided into direct and indirect effects. Due to its single structural component, the chemical composition is mainly a direct action on the part, with almost no indirect effect, and no multi-function, two-way (phase) and overall regulation. Natural Chinese herbs are all organic compounds, and each substance contains dozens of ingredients, so its role not only has a direct effect, but also has indirect effects and overall regulation. For example, astragalus contains as many as 14 trace elements, and Aconitum contains dozens of alkaloids. These components have a complex effect in addition to the single components, and they have a compound effect between them. This is unmatched by chemical compounds. . In each complex of natural Chinese herbal medicines, its binding mechanism is based on overall regulation of the mechanism of action, highlighting the corresponding effects on the body's interior and body and environment, and regulating their balance. Formula Principle and Development Trend of Natural Chinese Herbal Feed Additives Formula principle The market needs, the effect is stable, reflects the characteristics, the formula should be refined, and the amount to be added should be small, and it must be in line with the principle of “mini, high efficiencyâ€. development trend The active ingredients (such as polysaccharides, stilbenes, alkaloids, volatile components, etc.) of natural Chinese herbs are extracted, isolated, and identified using modern phytochemistry and instrumental analysis methods. Further research is conducted on the mechanism of action of natural herbal active ingredients, combining modern medicine, digestive physiology, metabolic utilization of nutrients, immunomodulatory mechanisms, and hormone secretion regulation to explore how natural Chinese herbs regulate homeostasis and improve intestinal microcirculation and Microbial flora, as well as immunoreactivity and other physiological and biochemical reactions in vivo. Strengthen the compatibility of natural Chinese herbal medicine and its synergistic mechanism. According to the different developmental stages and production purposes of the animals, specific specific additives for the production of refined special types are developed for different feeding conditions. Strengthen quality control of finished products and raw materials, as well as toxicological safety studies. Products must be industrialized, standardized, and participate in international market competition. Natural Chinese herbal feed additive is a kind of industry with strong vitality and has a very broad prospect of development.
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