Pharmacological effects 1, phlegm and asthma The volatile oil contained in this product has a limulus effect, and its active ingredient is limonene. Anesthetized cats were intravenously injected with hydroxyfulaline oxalate 1 mg/kg obtained from the Qingpi methanol extract to completely resist histamine-induced bronchoconstriction, and the effect lasted for about 1 hour. The guinea pig isolated trachea also has a strong relaxation effect and the role of anti-histamine contraction trachea, but the duration is short. 2, the role of smooth muscle Qingpi injection can reduce the tension contraction of the guinea pig's stomach, intestine, gallbladder and mouse uterus, and make the bladder smooth muscle excited. The acetylcholine-induced guinea pig isolated stomach, intestines and rabbits in the body of gastric smooth muscle and carbachol-induced gallbladder contraction, there is a significant role in spasmolysis. The histamine-induced guinea pig isolated intestinal and salicylic acid salicylate induced rabbit intestinal tension in the contraction, a significant inhibitory effect. It can resist the uterine tension contraction induced by pituitrin in the mouse. Excitatory effects on guinea pig in vivo bladder and rabbit aortic strips are mainly through excitatory adrenergic α receptors, and the aorta's excitatory effect is weaker than that of noradrenaline. Can significantly antagonize the guinea pig lung due to histamine-induced reduction in perfusion, and can lift the pharyngeal effect of histamine on the bronchial chain. It also significantly increases the bile flow in rats and increases biliary tone. 3, boost pressure Qingpi Decoction and Alcohol Decoction Injection injected intravenously into anesthetized cats, rabbits and rats, all have significant pressure-raising effects and can be excited to breathe. Repeated administration over a short period of time can produce rapid tolerance. In other ways, the boosting effect was not obvious. The boosting properties and strength of 1 g (TCM)/kg Peel injection are similar to those of 10 mcg/kg norepinephrine, but the duration of maintenance is longer. Intravenous injection at this dose for a variety of experimental shocks such as hemorrhagic shock, traumatic shock, E. coli endotoxin shock, pentobarbital sodium, or powder impeller impervious to total toxic shock, and canine due to input of anticoagulant rabbits Blood-induced shock has a therapeutic effect. Although there was no therapeutic effect on anaphylactic shock in rabbits with histamine shock, rabbits and guinea pigs, pre-administration had certain protective effects. In the composition obtained from ethyl acetate, 15 mg/kg intravenous injection also had a similar boosting effect to the injection. Pre-administration of hexahydrocarbyl quaternary ammonium, reserpine or propranolol did not affect its boosting effect, but it could be blocked by tolasurin or phenoxybenzamine, suggesting that the rind extract is an alpha-receptor stimulant. 4, anti-shock effect In dogs, cats, rabbits, and rats, many animals cause traumatic shock, transfusional shock, shock caused by overdose of Chinese herbal muscle relaxant (powder impeller total alkaloids), endotoxin shock, and anesthesia and hypnotic drug poisoning. All of them achieved significant curative effect with Qingpi injection; they had certain protective and preventive effects on acute anaphylactic shock and histamine shock in guinea pigs and rabbits. Pumpkin Kernel,Kernel Pumpkin Seed,Squash Seed Kernels,Roasted Pumpkin Seed Kernels Wuyuan county dafeng oil food co.,ltd , https://www.sundafengfoods.com